The Reds wasted little time asserting their authority with a goal inside the 10th minute to immediately take control of the match in Tehran’s Azadi Stadium.
Ali Alipour scored his 15th goal for Persepolis just 10 minutes into the match with a powerful left-footed strike from the edge of the box.
Former Sepahan defender Shoja Khalilzadeh extended the lead in the 68th minute, finding the back of the net with a header.
“I am very satisfied with the performance we did. We could have scored more goals and I think Persepolis were deserved to win the match,” Persepolis coach Branko Ivankovic said in the post-match news conference.
Persepolis moved clear 15 points at top of the table with 51 points.
Foolad sit in second place with 36 points but the Ahvaz-based team have two matches in hands.